kikimekikime
1.

The observable result or impact produced by a particular action or substance, often referring to the effectiveness of a remedy or advice.

2.

The characteristic quality or beneficial aspect of something, particularly in the context of how well it performs its intended function or achieves desired outcomes.

3.

A notable influence or impression left by a certain experience or interaction, highlighting the degree to which something has made a difference or brought about change.

Example:

その薬の効きめが現れた。