もはや最早mohaya
1.

Indicates a point in time that has arrived sooner than expected, often implying a sense of urgency or inevitability about a situation that has noticeably progressed or changed.

2.

Refers to a state in which the previous circumstances can no longer be applied, suggesting that a significant transformation has taken place that renders earlier conditions or beliefs obsolete.

Example:

もはや言うことはない。