ほろhoroぼすbosuほろhoroぼすbosu
1.

To cause the complete destruction or annihilation of something, rendering it nonexistent or eliminated.

2.

To bring about the downfall or collapse of a nation or entity, leading to its cessation of existence.

3.

To ruin one's own condition or state, resulting in self-sabotage or personal demise.

4.

To obliterate or eliminate something, leaving no trace or remnants behind.

Example:

核兵器はわが地球を滅ぼすと思う。

uchiほろhoroぼすbosu
1.

To invade and completely annihilate the opponent.

2.

To attack with the intent of causing total destruction.

3.

To vanquish an adversary by overpowering and offering no chance of recovery.