くる苦kuruしめるshimeru
1.
To place someone in a state of distress or agony, causing them to experience intense physical or emotional suffering.
2.
To impose difficulties or challenges on someone, leading to worry or trouble in their life.
3.
To subject someone to torment or anguish, often through persistent or harsh means, which can be physical, mental, or emotional.
4.
To bring about a sense of helplessness or discomfort in another person, often through bullying or oppressive actions.
Example:
その事実が彼女の心を苦し めている。