ついtsuiniついtsuini
1.

The culmination of various twists and turns leading to the expected final outcome or event after a considerable passage of time.

2.

The realization that an anticipated event or situation did not occur, often despite expectations or hope, resulting in an unfulfilled conclusion.

3.

A term used to denote the final moment or conclusion after a prolonged period or a series of events.

Example:

ついに病気で疲れた男たちは彼が待っている山岳都市に到着した。